Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323662 | 0.80 | MAPT (0.67) | MAPTALDH1A1RECQLHTTSMN1; SMN2 | |
| SCHEMBL4435949 | 0.79 | MAPT (0.63) | MAPTALDH1A1RECQLHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5326598 | 0.79 | MAPT (0.66) | MAPTALDH1A1RECQLHTTSMN1; SMN2 | |
| SCHEMBL5483633 | 0.79 | MAPT (0.65) | MAPTALDH1A1RECQLHTTSMN1; SMN2 | |
| SCHEMBL31557643 | 0.76 | CYP24A1 (0.49) | MAPTALDH1A1SMN1; SMN2MAPK1GAA | |
| SCHEMBL12643176 | 0.76 | MAPT (0.74) | MAPTALDH1A1RECQLHTTSMN1; SMN2 | |
| SCHEMBL14376967 | 0.76 | MAPT (0.62) | MAPTALDH1A1RECQLHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15819898 | 0.75 | MAPT (0.61) | MAPTALDH1A1RECQLHTTSMN1; SMN2 | |
| SCHEMBL9385318 | 0.75 | ALDH1A1 (0.51) | MAPTALDH1A1HTTSMN1; SMN2MAPK1 | |
| SCHEMBL29559830 | 0.75 | ALDH1A1 (0.51) | MAPTALDH1A1HTTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218352-B1 | BENZIMIDAZOLONE DERIVATIVES HAVING MIXED SEROTONINE AND DOPAMINE RECEPTORS AFFINITY | BOEHRINGER INGELHEIM ITALIA (IT) | 2004-05-12 | — | — | EP | disclosed |