Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062011 | 0.89 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5483633 | 0.86 | MAPT (0.65) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| SCHEMBL5323662 | 0.84 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| Hydrochloric Acid SCHEMBL5326598 | 0.83 | MAPT (0.66) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| SCHEMBL14376967 | 0.83 | MAPT (0.62) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| Hydrochloric Acid SCHEMBL15819898 | 0.82 | MAPT (0.61) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| SCHEMBL19030042 | 0.81 | MAPT (0.58) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| SCHEMBL259406 | 0.81 | MAPT (0.69) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL4435949 | 0.81 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| SCHEMBL4255526 | 0.81 | MAPT (0.76) | MAPTALDH1A1LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199589-A1 | PYRIMIDINE DERIVATIVES | 南京明德新药研发有限公司 | 2022-09-29 | — | — | WO | disclosed |
| EP-2327677-A1 | Mono-nitration of aromatic compounds | F. Hoffmann-La Roche AG (CH) | 2011-06-01 | — | — | EP | disclosed |
| US-7429589-B2 | Mono-nitration of aromatic compounds via nitrate salts | HOFFMANN-LA ROCHE INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429589-B2 | Mono-nitration of aromatic compounds via nitrate salts | HOFFMANN-LA ROCHE INC. (US) | 2008-09-30 | — | — | US | disclosed |
| WO-2007125034-A2 | MONO-NITRATION OF AROMATIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-11-08 | — | — | WO | disclosed |
| US-20070255057-A1 | Mono-nitration of aromatic compounds via nitrate salts | CEDILOTE MIALL | 2007-11-01 | — | — | US | disclosed |
| US-20070255057-A1 | Mono-nitration of aromatic compounds via nitrate salts | CEDILOTE MIALL | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070255057-A1 | Mono-nitration of aromatic compounds via nitrate salts | NOS2, NOS3, NOS1 | MAPT 1554/4885ALDH1A1 722/4885LMNA 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.