Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 15/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.46 |
| ▸ | PDE4A | P27815 | 9/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606335 | 0.88 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CERBB2 | |
| SCHEMBL6609750 | 0.84 | PDE4B (0.44) | PDE4DPDE4BPDE4APDE4CERBB2 | |
| SCHEMBL6606739 | 0.82 | PDE4A (0.46) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6607633 | 0.79 | PDE4D (0.51) | PDE4DPDE4BPDE4APDE4CCHEK1 | |
| SCHEMBL7361106 | 0.79 | PDE4D (0.51) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7357361 | 0.77 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7152154 | 0.77 | PDE4D (0.47) | PDE4DPDE4BPDE4APDE4CERBB2 | |
| SCHEMBL6606093 | 0.75 | PDE4B (0.44) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL27278144 | 0.75 | ALDH1A1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL9687781 | 0.74 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5935977-A | PHOSPHODIESTERASE IV INHIBITORS, TUMOR NECROSIS FACTOR-ALPHA PRODUCTION INHIBITORS; TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |