Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162376 | 0.92 | ALOX5 (0.59) | ALOX5MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2491580 | 0.89 | NPC1 (0.54) | NPC1ALOX5MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2723920 | 0.87 | TSHR (0.53) | NPC1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL3659810 | 0.85 | MAPT (0.50) | NPC1ALOX5MAPTALDH1A1SMN1; SMN2 | |
| Phenylboronic Acid SCHEMBL6611114 | 0.84 | ALOX5 (0.51) | ALOX5MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1997115 | 0.84 | NPC1 (0.70) | NPC1ALOX5MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7100948 | 0.84 | NPC1 (0.66) | NPC1MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8413415 | 0.84 | HTT (0.56) | NPC1ALOX5MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8413418 | 0.81 | HTT (0.51) | ALOX5MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL311833 | 0.80 | MEN1 (0.53) | ALOX5MAPTSMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379516-A1 | ALKOXYCARBONYLAMINO BENZOIC ACID OR ALKOXYCARBONYLAMINO TETRAZOLYL PHENYL DERIVATIVES AS IP ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002070500-A1 | ALKOXYCARBONYLAMINO BENZOIC ACID OR ALKOXYCARBONYLAMINO TETRAZOLYL PHENYL DERIVATIVES AS IP ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-09-12 | — | — | WO | disclosed |