Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744809 | 0.89 | TBXAS1 (0.50) | TBXAS1ACHEPRKCIQPCTCYP19A1 | |
| SCHEMBL19596990 | 0.84 | ACHE (0.64) | TBXAS1ACHEPRKCIQPCT | |
| SCHEMBL7739959 | 0.84 | ACHE (0.64) | TBXAS1ACHEPRKCIQPCT | |
| SCHEMBL6600770 | 0.83 | ACHE (0.49) | TBXAS1ACHEPRKCIQPCTCYP19A1 | |
| SCHEMBL13334889 | 0.81 | TBXAS1 (0.65) | TBXAS1ACHEPRKCIQPCTCYP19A1 | |
| SCHEMBL28158069 | 0.81 | TBXAS1 (0.55) | TBXAS1ACHEPRKCIQPCT | |
| SCHEMBL6601932 | 0.81 | TBXAS1 (0.55) | TBXAS1ACHEPRKCIQPCT | |
| SCHEMBL9777196 | 0.80 | TBXAS1 (0.85) | TBXAS1PRKCICYP19A1 | |
| SCHEMBL29284773 | 0.78 | TBXAS1 (0.52) | TBXAS1ACHEPRKCIQPCT | |
| Ammonia Solution, Strong SCHEMBL7096678 | 0.78 | TBXAS1 (0.81) | TBXAS1PRKCICYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |