Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744809 | 0.93 | TBXAS1 (0.50) | ACHETBXAS1EGLN3CYP2B6QPCT | |
| SCHEMBL11011577 | 0.86 | ACHE (0.60) | ACHETBXAS1EGLN3CYP2B6FPR3 | |
| SCHEMBL8699805 | 0.84 | ACHE (0.59) | ACHETBXAS1EGLN3CYP2B6ALOX15 | |
| SCHEMBL6607188 | 0.83 | TBXAS1 (0.57) | ACHETBXAS1QPCTCYP19A1PRKCI | |
| Hydrochloric Acid SCHEMBL28306929 | 0.82 | ACHE (0.57) | ACHETBXAS1EGLN3CYP2B6ALOX15 | |
| SCHEMBL6593644 | 0.75 | HRH3 (0.42) | SIGMAR1 | |
| SCHEMBL4758301 | 0.75 | TBXAS1 (0.50) | ACHETBXAS1EGLN3 | |
| SCHEMBL8510756 | 0.75 | TBXAS1 (0.50) | ACHETBXAS1EGLN3PRKCI | |
| SCHEMBL19596990 | 0.74 | ACHE (0.64) | ACHETBXAS1CYP2B6ALOX15FPR3 | |
| SCHEMBL591937 | 0.74 | TBXAS1 (0.48) | ACHETBXAS1EGLN3QPCTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |