Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606805 | 0.91 | MASP2 (0.33) | PPARGPPARA | |
| SCHEMBL6608416 | 0.88 | PPARG (0.34) | PPARGPPARAMEN1NPC1TP53 | |
| SCHEMBL6604993 | 0.86 | MEN1 (0.31) | MEN1NPC1TP53RAB9AKMT2A | |
| SCHEMBL6605583 | 0.85 | TRPM8 (0.40) | PPARGPPARAKMT2ASMN1; SMN2 | |
| SCHEMBL6400585 | 0.83 | TRPM8 (0.38) | PPARGPPARA | |
| SCHEMBL6398852 | 0.79 | AOC3 (0.35) | PPARGPPARAMEN1NPC1TP53 | |
| SCHEMBL6605212 | 0.78 | PPARG (0.32) | PPARGPPARA | |
| SCHEMBL6609993 | 0.77 | SCN9A (0.35) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL6399472 | 0.76 | MASP2 (0.33) | — | |
| SCHEMBL6431116 | 0.71 | TRPM8 (0.39) | MEN1TP53KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |