Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608416 | 0.91 | PPARG (0.34) | PPARGPPARA | |
| SCHEMBL6606805 | 0.87 | MASP2 (0.33) | PPARGPPARAPPARDHTR2CSLC6A4 | |
| SCHEMBL6609993 | 0.87 | SCN9A (0.35) | PPARGPPARAPPARD | |
| SCHEMBL6403984 | 0.85 | MMP13 (0.30) | — | |
| SCHEMBL6605583 | 0.80 | TRPM8 (0.40) | PPARGPPARAPPARD | |
| SCHEMBL6607189 | 0.78 | PPARG (0.33) | PPARGPPARA | |
| SCHEMBL6400585 | 0.77 | TRPM8 (0.38) | PPARGPPARAPPARDHTR2C | |
| SCHEMBL6399629 | 0.76 | ADORA2A (0.31) | — | |
| SCHEMBL6404188 | 0.75 | NPC1 (0.34) | — | |
| SCHEMBL6399472 | 0.72 | MASP2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |