Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | FCER2 | P06734 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611582 | 0.93 | TRPV1 (0.45) | CYP1A2TRPV1LMNAPOLBTSHR | |
| SCHEMBL6608485 | 0.89 | MMP2 (0.48) | CYP1A2TRPV1LMNAPOLBTSHR | |
| SCHEMBL6608602 | 0.87 | KDM4E (0.43) | CYP1A2TRPV1TSHRRAB9AHSD17B10 | |
| SCHEMBL6606296 | 0.86 | MMP2 (0.48) | CYP1A2LMNAPOLBTSHRRAB9A | |
| SCHEMBL6079755 | 0.82 | KMT2A (0.42) | CYP1A2MMP2MMP13MMP9MMP1 | |
| SCHEMBL6611575 | 0.81 | CYP1A2 (0.41) | CYP1A2TRPV1LMNAPOLBTSHR | |
| SCHEMBL6611578 | 0.81 | CYP1A2 (0.41) | CYP1A2TRPV1LMNAPOLBTSHR | |
| SCHEMBL6401583 | 0.78 | RAB9A (0.40) | CYP1A2TRPV1LMNAPOLBTSHR | |
| SCHEMBL6989873 | 0.77 | KMT2A (0.44) | CYP1A2MMP2MMP13MMP9MMP1 | |
| SCHEMBL6607276 | 0.76 | CYP1A2 (0.42) | CYP1A2TRPV1LMNAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |