Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432214 | 0.74 | CA12 (0.46) | DHODHALDH1A1CYP3A4PKMCNR2 | |
| SCHEMBL25403099 | 0.73 | ALDH1A1 (0.45) | DHODHALDH1A1CYP3A4PKMCNR2 | |
| SCHEMBL1032100 | 0.72 | ALDH1A1 (0.44) | DHODHALDH1A1CYP3A4PKMCNR2 | |
| SCHEMBL1031704 | 0.72 | ALDH1A1 (0.44) | DHODHALDH1A1CYP3A4PKMCNR2 | |
| SCHEMBL1031702 | 0.72 | ALDH1A1 (0.44) | DHODHALDH1A1CYP3A4PKMCNR2 | |
| SCHEMBL4920359 | 0.71 | PKM (0.53) | DHODHALDH1A1PKMSTAT3VDR | |
| SCHEMBL2545829 | 0.71 | PKM (0.53) | DHODHALDH1A1PKMSTAT3VDR | |
| SCHEMBL1206501 | 0.71 | PKM (0.53) | DHODHALDH1A1PKMSTAT3VDR | |
| SCHEMBL13075431 | 0.71 | TACR1 (0.47) | ALDH1A1PKMVDR | |
| SCHEMBL14037088 | 0.71 | TACR1 (0.47) | ALDH1A1PKMVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |