Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206501 | 1.00 | PKM (0.53) | PKMLMNADHODHALDH1A1STAT3 | |
| SCHEMBL2545829 | 1.00 | PKM (0.53) | PKMLMNADHODHALDH1A1STAT3 | |
| SCHEMBL2539995 | 0.92 | PKM (0.44) | PKMDHODHALDH1A1STAT3CYP2D6 | |
| SCHEMBL6980265 | 0.92 | PKM (0.44) | PKMDHODHALDH1A1STAT3CYP2D6 | |
| SCHEMBL6980159 | 0.87 | PKM (0.41) | PKMDHODHALDH1A1STAT3HTT | |
| SCHEMBL4432214 | 0.86 | CA12 (0.46) | PKMLMNADHODHALDH1A1STAT3 | |
| SCHEMBL3181029 | 0.85 | ALDH1A1 (0.42) | PKMLMNAALDH1A1HTTKMT2A | |
| SCHEMBL1463518 | 0.85 | PKM (0.51) | PKMLMNADHODHALDH1A1STAT3 | |
| SCHEMBL1463520 | 0.85 | PKM (0.51) | PKMLMNADHODHALDH1A1STAT3 | |
| SCHEMBL2545371 | 0.85 | UTS2R (0.42) | PKMLMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260000642-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | TAY THERAPEUTICS LTD (GB) | 2026-01-01 | — | — | US | disclosed |
| US-20250263370-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | Tay Therapeutics Limited (GB) | 2025-08-21 | — | — | US | disclosed |
| EP-4558224-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | Tay Therapeutics Limited (GB) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024018423-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | Tay Therapeutics Limited (GB) | 2024-01-25 | — | — | WO | disclosed |
| CN-112962165-B | Spandex fiber with reversible three-shape memory effect and preparation method and application thereof | 五邑大学 | 2022-07-05 | — | — | CN | disclosed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| CN-112962165-A | Spandex fiber with reversible three-shape memory effect and preparation method and application thereof | 五邑大学 | 2021-06-15 | — | — | CN | disclosed |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2019-10-08 | — | — | US | disclosed |
| US-20190046515-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2019-02-14 | — | — | US | disclosed |
| US-6130346-A | ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION | MITSUI CHEMICALS, INC. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0950649-A1 | A process for preparing oxyalkylene derivatives in the presence of phosphine oxides | Mitsui Chemicals, Inc. (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0934264-A1 | PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS | PFIZER INC. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998012177-A1 | PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS | PFIZER INC. (JP) | 1998-03-26 | — | — | WO | disclosed |
| US-4845127-A | ANTIBESITY | ELI LILLY AND COMPANY (US) | 1989-07-04 | — | — | US | disclosed |
| EP-0055059-B1 | DIAZOLE AND TRIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTI-MICROBIAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1985-03-27 | — | — | EP | disclosed |
| US-4421758-A | FUNGICIDES | SANKYO COMPANY LIMITED (JP) | 1983-12-20 | — | — | US | disclosed |
| US-4391826-A | DIETETICS | ELI LILLY AND COMPANY (US) | 1983-07-05 | — | — | US | disclosed |
| EP-0006766-B1 | PHENETHANOLAMINES, THEIR FORMULATIONS, USE AND PREPARATION | ELI LILLY AND COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| EP-0007204-B1 | PHENETHANOLAMINES, THEIR FORMULATIONS, USE AND PREPARATION | ELI LILLY AND COMPANY (US) | 1982-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, MRPS18A | PKM 2597/4885LMNA 4044/4885DHODH 2809/4885 |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, COG8 | PKM 2147/4885LMNA 3900/4885DHODH 2507/4885 |
| US-20190046515-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | NOX1, NOX5, CYBB | PKM 1786/4885LMNA 4266/4885DHODH 56/4885 |
| US-20260000642-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | BET1, BRD4, PHKB | PKM 4715/4885LMNA 3175/4885DHODH 4542/4885 |
| US-20250263370-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | BET1, PHKB, BRD4 | PKM 3700/4885LMNA 4331/4885DHODH 3820/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | PKM 1929/4885LMNA 826/4885DHODH 3429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.