Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607289 | 0.88 | MMP2 (0.36) | CYP2A6MMP2MMP13TRPV3TPSAB1 | |
| SCHEMBL6399773 | 0.88 | CYP2A6 (0.43) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6400628 | 0.88 | CYP2A6 (0.43) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6404068 | 0.84 | CYP2A6 (0.44) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6406503 | 0.81 | CYP2A6 (0.50) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6406508 | 0.81 | CYP2A6 (0.50) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6607282 | 0.78 | CYP2A6 (0.33) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6403067 | 0.77 | CYP2A6 (0.38) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6608461 | 0.77 | CYP2A6 (0.38) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6406203 | 0.77 | CA2 (0.38) | CYP2A6MMP13CA2CA12PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |