Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 6/20 | 0.35 |
| ▸ | MMP9 | P14780 | 5/20 | 0.35 |
| ▸ | MMP1 | P03956 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.34 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.34 |
| ▸ | RPS17 | P08708 | 1/20 | 0.34 |
| ▸ | RPSA | P08865 | 1/20 | 0.34 |
| ▸ | RPS2 | P15880 | 1/20 | 0.34 |
| ▸ | RPL35A | P18077 | 1/20 | 0.34 |
| ▸ | RPL7 | P18124 | 1/20 | 0.34 |
| ▸ | RPL17 | P18621 | 1/20 | 0.34 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.34 |
| ▸ | RPS3 | P23396 | 1/20 | 0.34 |
| ▸ | RPS12 | P25398 | 1/20 | 0.34 |
| ▸ | RPL13 | P26373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605969 | 0.85 | SLC6A2 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6605965 | 0.85 | SLC6A2 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6605208 | 0.84 | SLC6A2 (0.36) | — | |
| SCHEMBL6605205 | 0.84 | SLC6A2 (0.36) | — | |
| SCHEMBL5971586 | 0.82 | REN (0.32) | MMP13RPLP1RPLP0RPS17RPSA | |
| SCHEMBL6589031 | 0.80 | — | — | |
| SCHEMBL4768704 | 0.72 | PSEN1 (0.39) | CAMK2AMMP3CAMK2GMMP13MMP9 | |
| SCHEMBL6610801 | 0.71 | MBTPS1 (0.34) | ALDH1A1GAA | |
| SCHEMBL6610800 | 0.71 | MBTPS1 (0.34) | ALDH1A1GAA | |
| SCHEMBL4212772 | 0.70 | CTSS (0.35) | MMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |