Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.58 |
| ▸ | CDK2 | P24941 | 3/20 | 0.58 |
| ▸ | CDK9 | P50750 | 15/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 14/20 | 0.49 |
| ▸ | CDK4 | P11802 | 14/20 | 0.49 |
| ▸ | CCND1 | P24385 | 14/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 14/20 | 0.49 |
| ▸ | CDK11A | Q9UQ88 | 13/20 | 0.49 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611369 | 0.82 | CDK5 (0.72) | CDK5MAPK1KMT2AMEN1NPC1 | |
| SCHEMBL6603770 | 0.82 | KMT2A (0.58) | CDK5MAPK1KMT2AMEN1NPC1 | |
| SCHEMBL6617607 | 0.76 | CDK5 (0.62) | CDK5MAPK1KMT2AMEN1NPC1 | |
| SCHEMBL6605716 | 0.73 | CDK5 (0.52) | CDK5MAPK1KMT2AMAPTHTT | |
| SCHEMBL7756151 | 0.73 | KMT2A (0.71) | CDK5MAPK1KMT2AMEN1NPC1 | |
| SCHEMBL7753417 | 0.69 | CCNA2 (0.68) | CDK5MAPK1KMT2AMEN1NPC1 | |
| SCHEMBL7432625 | 0.67 | KMT2A (0.56) | MAPK1KMT2AMEN1MAPTGSK3B | |
| SCHEMBL4257980 | 0.66 | FPR3 (0.45) | KMT2AMAPTHTTLMNA | |
| SCHEMBL6755564 | 0.65 | CDK5 (0.56) | CDK5MAPK1KMT2AMEN1NPC1 | |
| SCHEMBL20618526 | 0.62 | KMT2A (0.74) | MAPK1KMT2AMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040210063-A1 | Novel 2,4-diaminothiazole derivatives | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | US | disclosed |
| EP-1417188-A1 | NOVEL 2,4-DIAMINOTHIAZOLE DERIVATIVES | Novo Nordisk A/S (DK) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003011843-A1 | NOVEL 2,4-DIAMINOTHIAZOLE DERIVATIVES | NOVO NORDISK A/S (DK) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210063-A1 | Novel 2,4-diaminothiazole derivatives | GSK3B, GSK3A, GYS2 | CDK5 749/4885MAPK1 189/4885KMT2A 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.