Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16923921 | 0.86 | POLB (0.40) | LOXAOC3HTR1AHTR7NAAA | |
| SCHEMBL674403 | 0.81 | CYP2D6 (0.47) | NAAAPOLBKDM4ECYP2D6CYP19A1 | |
| SCHEMBL897482 | 0.78 | CYP2D6 (0.49) | HTR1AHTR7NAAAPOLBKDM4E | |
| SCHEMBL14300674 | 0.78 | LTA4H (0.37) | HTR1AHTR7NAAAPOLBLTA4H | |
| SCHEMBL6708682 | 0.76 | NAAA (0.39) | HTR1AHTR7NAAALTA4HPTGS2 | |
| SCHEMBL4273388 | 0.76 | CYP2D6 (0.54) | HTR1AHTR7NAAALTA4HPTGS2 | |
| SCHEMBL18263363 | 0.76 | NAAA (0.39) | HTR1AHTR7NAAALTA4HPTGS2 | |
| SCHEMBL29415405 | 0.74 | NAAA (0.41) | HTR1AHTR7NAAALTA4HPTGS2 | |
| SCHEMBL18076195 | 0.74 | NAAA (0.39) | HTR1AHTR7NAAALTA4HPTGS2 | |
| SCHEMBL4278696 | 0.74 | CYP2D6 (0.43) | HTR1AHTR7NAAALTA4HPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-B1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |