Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236416 | 0.98 | CYP2D6 (0.47) | CYP2D6CYP2C9CYP2C19CYP19A1CYP3A4 | |
| SCHEMBL674403 | 0.98 | CYP2D6 (0.47) | CYP2D6CYP2C9CYP2C19CYP19A1CYP3A4 | |
| SCHEMBL4273388 | 0.94 | CYP2D6 (0.54) | CYP2D6CYP2C9CYP2C19CYP19A1CYP3A4 | |
| SCHEMBL4278696 | 0.88 | CYP2D6 (0.43) | CYP2D6CYP2C9CYP2C19CYP19A1CYP3A4 | |
| SCHEMBL30339345 | 0.88 | CYP2D6 (0.43) | CYP2D6CYP2C9CYP2C19CYP19A1CYP3A4 | |
| Heptane SCHEMBL9236410 | 0.84 | KDM4E (0.45) | CYP2D6CYP2C9CYP2C19CYP19A1CYP3A4 | |
| SCHEMBL31462005 | 0.81 | NAAA (0.39) | CYP2D6CYP2C9CYP2C19CYP19A1CYP3A4 | |
| SCHEMBL29415405 | 0.80 | NAAA (0.41) | CYP2D6CYP2C9CYP2C19CYP19A1KDM4E | |
| SCHEMBL18076195 | 0.79 | NAAA (0.39) | CYP2D6CYP2C9CYP2C19CYP19A1KDM4E | |
| SCHEMBL1692005 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3884018-A1 | JASMOL | Symrise AG (DE) | 2021-09-29 | — | — | EP | claimed |
| US-9012096-B2 | Long life lithium batteries with stabilized electrodes | UCHICAGO ARGONNE, LLC (US) | 2015-04-21 | — | — | US | claimed |
| US-7851092-B2 | Redox shuttles for overcharge protection of lithium batteries | U CHICAGO ARGONNE LLC (US) | 2010-12-14 | — | — | US | claimed |
| WO-2006094069-A2 | NOVEL REDOX SHUTTLES FOR OVERCHARGE PROTECTION OF LITHIUM BATTERIES | UCHICAGO ARGONNE, LLC (US) | 2006-09-08 | — | — | WO | claimed |
| US-20060199080-A1 | Novel redox shuttles for overcharge protection of lithium batteries | THE UNIVERSITY OF CHICAGO | 2006-09-07 | — | — | US | claimed |
| US-20060147809-A1 | Non-aqueous electrolyte of an alkali metal salt, a polar aprotic solvent, and an electrode stabilization additive comprising a linear, branched or cyclic hydrocarbon, other than a spirocyclic hydrocarbon, comprising at least one oxygen atom and at least one aryl, alkenyl or alkynyl group | THE UNIVERSITY OF CHICAGO | 2006-07-06 | — | — | US | claimed |
| US-12021226-B2 | Cathode materials for secondary batteries | UCHICAGO ARGONNE, LLC (US) | 2024-06-25 | — | — | US | disclosed |
| EP-3656009-B1 | MODIFIED IONIC LIQUIDS CONTAINING TRIAZINE | NOHMS TECH INC (US) | 2023-11-15 | — | — | EP | disclosed |
| EP-4158671-A2 | MODIFIED IONIC LIQUIDS CONTAINING BICYCLOPHOSPHATE MOIETY | Nohms Technologies, Inc. (US) | 2023-04-05 | — | — | EP | disclosed |
| US-11575125-B2 | Patterned anode for lithium-ion batteries | UCHICAGO ARGONNE, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| EP-4106070-A1 | PHOSPHORUS-CONTAINING ELECTROLYTES | Nohms Technologies, Inc. (US) | 2022-12-21 | — | — | EP | disclosed |
| US-11489201-B2 | Modified ionic liquids containing phosphorus | NOHMs Technologies, Inc. (US) | 2022-11-01 | — | — | US | disclosed |
| EP-3436465-B1 | MODIFIED IONIC LIQUIDS CONTAINING PHOSPHORUS | NOHMS TECH INC (US) | 2022-05-25 | — | — | EP | disclosed |
| EP-1539736-A1 | SUBSTITUTED 1,4-PYRAZINE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20050049257-A1 | Substituted aryl 1, 4-pyrazine derivatives | PFIZER INC | 2005-03-03 | — | — | US | disclosed |
| EP-1446387-A1 | SUBSTITUTED ARYL 1,4-PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2004-08-18 | — | — | EP | disclosed |
| US-20040116444-A1 | Substituted 1,4-pyrazine derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-17 | — | — | US | disclosed |
| WO-2004024719-A1 | SUBSTITUTED 1,4-PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-25 | — | — | WO | disclosed |
| US-20030144297-A1 | Substituted aryl 1,4-pyrazine derivatives | PHARMACIA & UPJOHN COMPANY | 2003-07-31 | — | — | US | disclosed |
| WO-2003045924-A1 | SUBSTITUTED ARYL 1,4-PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049257-A1 | Substituted aryl 1, 4-pyrazine derivatives | HTR2C, HTR4, HTR5A | CYP2D6 311/4885CYP2C9 992/4885CYP2C19 229/4885 |
| US-11489201-B2 | Modified ionic liquids containing phosphorus | INPPL1, PLCB3, INPP5D | CYP2D6 3872/4885CYP2C9 3774/4885CYP2C19 3927/4885 |
| US-20030144297-A1 | Substituted aryl 1,4-pyrazine derivatives | HTR2C, HTR4, HTR5A | CYP2D6 311/4885CYP2C9 992/4885CYP2C19 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.