Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 9/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606739 | 0.87 | PDE4A (0.46) | PDE4BPDE4APDE4CPDE4DPDGFRB | |
| SCHEMBL8399368 | 0.86 | POLB (0.47) | POLBPDE4BPDE3APDE4APDE4C | |
| SCHEMBL6605813 | 0.82 | POLB (0.44) | POLBPDE4BPDE3APDE4APDE4C | |
| SCHEMBL72368 | 0.74 | PDE4A (0.50) | POLBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7148127 | 0.70 | PDE4A (0.47) | PDE4BPDE4APDE4CPDE4DPDGFRB | |
| SCHEMBL6606836 | 0.70 | PDE4D (0.46) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL24509871 | 0.70 | ALDH1A1 (0.36) | POLBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9784650 | 0.70 | KDM4E (0.39) | POLBKDM4EALDH1A1 | |
| SCHEMBL6605575 | 0.69 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DPDGFRB | |
| SCHEMBL682485 | 0.69 | POLB (0.57) | POLBPDE4BPDE3APDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169792-C | Substituted vinylpyridine derivatives and medicaments containing them | ������ҩ��ʽ���� | 2004-10-06 | — | — | CN | disclosed |
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5935977-A | PHOSPHODIESTERASE IV INHIBITORS, TUMOR NECROSIS FACTOR-ALPHA PRODUCTION INHIBITORS; TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |