SCHEMBL682485

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL705028	0.97	POLB (0.57)	POLBNPY1RNPY2RPDE4BPDE3A
	SCHEMBL129356	0.82	PDE4A (0.59)	POLBNPY1RNPY2RPDE4BPDE4A
	SCHEMBL128455	0.82	NPY1R (0.50)	POLBNPY1RNPY2RSLC6A4HTR6
	SCHEMBL5704271	0.81	PDE4A (0.57)	POLBNPY1RNPY2RPDE4BPDE4A
	SCHEMBL182753	0.79	TSHR (0.56)	POLBPDE3AHPGDTSHRPDE4A
	SCHEMBL31096231	0.79	TSHR (0.56)	POLBPDE3AHPGDTSHRPDE4A
	SCHEMBL7376963	0.79	HTT (0.52)	POLBPDE4BPDE3APDE4APDE4C
	SCHEMBL130569	0.79	PDE4A (0.55)	POLBNPY1RNPY2RPDE4BPDE4A
	SCHEMBL133005	0.78	PDE4A (0.50)	POLBNPY1RNPY2RPDE4BSLC6A4
	SCHEMBL31096114	0.78	PDE4A (0.50)	POLBNPY1RNPY2RPDE4BSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.