Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599023 | 0.86 | HTR1A (1.00) | HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6597603 | 0.85 | HTR1A (0.98) | HTR1AHTR1D | |
| SCHEMBL6598541 | 0.76 | HTR1A (0.65) | HTR1AHTR1D | |
| SCHEMBL6598942 | 0.75 | HTR1A (1.00) | HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6599712 | 0.74 | HTR1A (0.98) | HTR1AALDH1A1MAPTGFERHTR1D | |
| SCHEMBL28185020 | 0.72 | HTR1A (0.73) | HTR1A | |
| SCHEMBL6598604 | 0.68 | HTR1A (0.68) | HTR1AHTR1D | |
| SCHEMBL6598764 | 0.67 | HTR1A (1.00) | HTR1AHTR1D | |
| SCHEMBL5470993 | 0.67 | GAA (0.58) | HTR1AALDH1A1MAPT | |
| SCHEMBL27910321 | 0.67 | HTR1A (0.52) | HTR1AHTR1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | disclosed |