Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607831 | 1.00 | MMP2 (0.39) | MMP2MMP13GAAALDH1A1KMT2A | |
| SCHEMBL6406851 | 0.91 | MMP2 (0.34) | MMP2MMP13GAAALDH1A1KMT2A | |
| SCHEMBL6406210 | 0.84 | CA2 (0.38) | MMP13ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL6406203 | 0.84 | CA2 (0.38) | MMP13ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL6397626 | 0.82 | CHEK1 (0.35) | MMP2MMP13GAAALDH1A1KMT2A | |
| SCHEMBL6397621 | 0.82 | CHEK1 (0.35) | MMP2MMP13GAAALDH1A1KMT2A | |
| SCHEMBL6406849 | 0.81 | ALDH1A1 (0.31) | MMP2MMP13ALDH1A1CA12CA2 | |
| SCHEMBL6400568 | 0.80 | — | — | |
| SCHEMBL6400628 | 0.77 | CYP2A6 (0.43) | MMP2MMP13CYP2A6CA12CA2 | |
| SCHEMBL6399773 | 0.77 | CYP2A6 (0.43) | MMP2MMP13CYP2A6CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |