Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 7/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670084 | 0.87 | CA2 (0.52) | RECQLCA2CA1CA9CA12 | |
| SCHEMBL11166463 | 0.82 | RECQL (0.96) | RECQLCA2CA1CA9CA12 | |
| SCHEMBL5725397 | 0.80 | RECQL (0.64) | RECQLCA2CA1CA9CA12 | |
| SCHEMBL1044703 | 0.80 | RECQL (0.64) | RECQLCA2CA1CA9CA12 | |
| SCHEMBL4769306 | 0.80 | RECQL (0.64) | RECQLCA2CA1CA9CA12 | |
| SCHEMBL29046728 | 0.80 | RECQL (0.64) | RECQLCA2CA1CA9CA12 | |
| SCHEMBL8113789 | 0.80 | RECQL (0.64) | RECQLCA2CA1CA9CA12 | |
| SCHEMBL1644097 | 0.79 | CA2 (0.70) | RECQLCA2CA1CA9CA12 | |
| Hydrochloric Acid SCHEMBL3516882 | 0.77 | CA2 (0.68) | RECQLCA2CA1CA9CA12 | |
| SCHEMBL4063879 | 0.77 | CA2 (0.68) | RECQLCA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368327-B1 | BENZO THIADIAZINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-10-20 | — | — | EP | claimed |