Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6607875 | 0.99 | ACHE (0.46) | ACHEBCHEHTR2AHTR2CHTR2B | |
| SCHEMBL6607314 | 0.80 | MAPT (0.56) | ACHEBCHEHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL6610212 | 0.79 | MAPT (0.58) | ACHEBCHEHTR2AHTR2CHTR2B | |
| SCHEMBL7976500 | 0.78 | ALDH1A1 (0.54) | ACHEBCHEHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL7976524 | 0.77 | ALDH1A1 (0.56) | ACHEBCHEHTR2AHTR2CHTR2B | |
| SCHEMBL18210521 | 0.70 | HTR2C (0.41) | HTR2AHTR2CHTR2BMAPTPOLB | |
| SCHEMBL11836752 | 0.70 | ALDH1A1 (0.51) | ACHEBCHEMAPTPOLBSMN1; SMN2 | |
| SCHEMBL1816256 | 0.69 | CYP3A4 (0.48) | ACHEHTR2AHTR2CHTR2BPOLB | |
| Hydrochloric Acid SCHEMBL11837304 | 0.69 | ALDH1A1 (0.53) | ACHEBCHEMAPTPOLBSMN1; SMN2 | |
| SCHEMBL11832472 | 0.67 | ALDH1A1 (0.55) | ACHEBCHEHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997462-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | claimed |
| EP-0997462-B1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | NIPPON KAYAKU KK (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-6294547-B1 | Naphthyridine deratives or salts thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0997462-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |