Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 4/20 | 0.33 |
| ▸ | MMP13 | P45452 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP7 | P09237 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17245263 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1CA12CA14LMNA | |
| SCHEMBL6608711 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1CA12CA14LMNA | |
| Hydrochloric Acid SCHEMBL626518 | 0.98 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1CA12CA14LMNA | |
| Hydrochloric Acid SCHEMBL626519 | 0.98 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1CA12CA14LMNA | |
| SCHEMBL15922140 | 0.87 | ALDH1A1 (0.35) | ALDH1A1TP53SLC6A3 | |
| SCHEMBL17169784 | 0.83 | TP53 (0.39) | ALDH1A1TP53SLC6A3 | |
| SCHEMBL3891997 | 0.83 | TP53 (0.39) | ALDH1A1TP53SLC6A3 | |
| SCHEMBL3272882 | 0.83 | TP53 (0.39) | ALDH1A1TP53SLC6A3 | |
| SCHEMBL3272876 | 0.83 | TP53 (0.39) | ALDH1A1TP53SLC6A3 | |
| Hydrochloric Acid SCHEMBL3653512 | 0.81 | TP53 (0.38) | SMN1; SMN2ALDH1A1TP53SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239879-A | Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine | 泰山学院 | 2024-06-25 | — | — | CN | claimed |
| CN-109928908-B | Preparation method and intermediate of drug-linker MC-MMAF for antibody drug conjugate | 联宁（苏州）生物制药有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-119470406-A | Phthalic dicarboxaldehyde disinfectant concentration detection test paper and preparation method thereof | 山东新华莎罗雅生物技术有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-118239879-A | Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine | 泰山学院 | 2024-06-25 | — | — | CN | disclosed |
| US-20220183291-A1 | COMPOSITIONS AND METHODS FOR MODULATING IMMUNITY IN PLANTS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. | 2022-06-16 | — | — | US | disclosed |
| CN-114466838-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2022-05-10 | — | — | CN | disclosed |
| CN-113924290-A | Thiohydrazinocarboxylic acid esters and their use | 范因斯坦医学研究院 | 2022-01-11 | — | — | CN | disclosed |
| CN-113816990-A | Modified amino acids and their use in ADCs | 联宁（苏州）生物制药有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-112543764-A | Amide compound with BET proteolysis induction effect and medical application thereof | 田边三菱制药株式会社 | 2021-03-23 | — | — | CN | disclosed |
| WO-2020242253-A1 | NOVEL EMPAGLIFLOZIN DERIVATIVE WHICH IS SGLT-2 INHIBITOR | 동아에스티 주식회사 | 2020-12-03 | — | — | WO | disclosed |
| CN-106316982-B | Thiazine amide derivative and use thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2020-08-14 | — | — | CN | disclosed |
| US-20030176445-A1 | Substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. | 2003-09-18 | — | — | US | disclosed |
| EP-1106615-B1 | Substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6444677-B2 | TREATMENT OF INFLAMMATION, CARDIOVASCULAR DISEASE, PAIN, ETC. | PFIZER INC. | 2002-09-03 | — | — | US | disclosed |
| US-20020042421-A1 | Substituted 1,4-dihydropyridine compounds as bradykinin antagonists | OKUMURA YOSHIYUKI (JP) | 2002-04-11 | — | — | US | disclosed |
| US-20010046993-A1 | 5-memberd heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | IKEDA TAKAFUMI (JP) | 2001-11-29 | — | — | US | disclosed |
| EP-1106614-A1 | 5-Membered heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1106615-A1 | Substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6156752-A | Optically active 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0899261-A1 | Optical active 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. (US) | 1999-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220183291-A1 | COMPOSITIONS AND METHODS FOR MODULATING IMMUNITY IN PLANTS | IFNG, STING1, IRF3 | SMN1; SMN2 4468/4885ALDH1A1 4576/4885CA12 3643/4885 |
| US-20030176445-A1 | Substituted 1,4-dihydropyridine compounds as bradykinin antagonists | BDKRB1, BDKRB2, HRH4 | SMN1; SMN2 4652/4885ALDH1A1 2124/4885CA12 3085/4885 |
| US-20010046993-A1 | 5-memberd heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | BDKRB1, BDKRB2, CNR2 | SMN1; SMN2 3038/4885ALDH1A1 2557/4885CA12 4513/4885 |
| US-20020042421-A1 | Substituted 1,4-dihydropyridine compounds as bradykinin antagonists | BDKRB1, BDKRB2, HRH4 | SMN1; SMN2 4681/4885ALDH1A1 1413/4885CA12 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.