Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607933 | 0.93 | HTR6 (0.38) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL6607627 | 0.92 | HTR6 (0.37) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6610824 | 0.91 | HTR6 (0.36) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6607562 | 0.89 | HTR6 (0.39) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6610032 | 0.89 | POLB (0.33) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL6608843 | 0.89 | HTR6 (0.37) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8133111 | 0.86 | HTR6 (0.42) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4401527 | 0.84 | HTR6 (0.43) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8133241 | 0.84 | HTR6 (0.43) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4393716 | 0.84 | HTR6 (0.43) | HTR6GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869958-B1 | NOVEL INDOLE-2,3-DIONE-3-OXIME DERIVATIVES | NEUROSEARCH AS (DK) | 2004-12-29 | — | — | EP | claimed |
| EP-1066037-B1 | USE OF INDOLE-2,3-DIONE-3-OXIME DERIVATIVES AS AMPA ANTAGONISTS | NEUROSEARCH AS (DK) | 2004-12-29 | — | — | EP | claimed |