Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923474 | 0.85 | RAB9A (0.46) | RAB9ANAMPTCTSSCTSKCYP3A4 | |
| SCHEMBL6608688 | 0.82 | CYP17A1 (0.44) | RAB9ANAMPTCTSSCTSKMAPT | |
| SCHEMBL1480134 | 0.82 | CTSS (0.50) | RAB9ANAMPTCTSSCTSKCYP3A4 | |
| SCHEMBL4148003 | 0.82 | CTSS (0.50) | RAB9ANAMPTCTSSCTSKCYP3A4 | |
| SCHEMBL4148011 | 0.82 | CTSS (0.50) | RAB9ANAMPTCTSSCTSKCYP3A4 | |
| SCHEMBL1194009 | 0.82 | CTSK (0.55) | CTSSCTSKMAPT | |
| SCHEMBL1193789 | 0.82 | CTSK (0.55) | CTSSCTSKMAPT | |
| SCHEMBL6609045 | 0.82 | CTSK (0.55) | CTSSCTSKMAPT | |
| SCHEMBL25222264 | 0.81 | RAB9A (0.47) | RAB9ANAMPTCTSSCTSKCYP3A4 | |
| SCHEMBL25269953 | 0.81 | RAB9A (0.47) | RAB9ANAMPTCTSSCTSKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | claimed |
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | claimed |
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1140895-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040576-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |