Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603947 | 0.85 | KDM4C (0.56) | KMT2AL3MBTL1MEN1HPGDSMN1; SMN2 | |
| SCHEMBL4303922 | 0.81 | NCEH1 (0.54) | KMT2AL3MBTL1MEN1SMN1; SMN2RAB9A | |
| SCHEMBL1495919 | 0.79 | MEN1 (0.66) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 | |
| Benzene SCHEMBL6364361 | 0.79 | MEN1 (0.66) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6605120 | 0.77 | ALDH1A1 (0.53) | KMT2AL3MBTL1MEN1HPGDSMN1; SMN2 | |
| SCHEMBL4781790 | 0.76 | LSS (0.74) | KMT2AL3MBTL1MEN1HPGDRAB9A | |
| SCHEMBL6603038 | 0.76 | CYSLTR2 (0.54) | KMT2AMEN1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL6608386 | 0.75 | KDM4E (0.52) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL5272168 | 0.75 | KMT2A (1.00) | KMT2AL3MBTL1MEN1HPGDSMN1; SMN2 | |
| SCHEMBL17141929 | 0.74 | KMT2A (0.59) | KMT2AL3MBTL1MEN1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | claimed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | claimed |
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | disclosed |