Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634541 | 0.86 | KMT2A (0.36) | RAB9ANPC1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL4607918 | 0.81 | KDM4E (0.36) | RAB9ANPC1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL27617435 | 0.79 | ESR1 (0.41) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL27997449 | 0.78 | LMNA (0.38) | RAB9ANPC1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL10872973 | 0.78 | KDM4E (0.41) | RAB9ALMNAHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL27673491 | 0.78 | LMNA (0.42) | RAB9ANPC1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL11459102 | 0.76 | KDM4E (0.38) | RAB9ANPC1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL27680682 | 0.76 | KMT2A (0.41) | RAB9ALMNAHSD17B10ALDH1A1MEN1 | |
| SCHEMBL27703251 | 0.76 | POLB (0.39) | RAB9ANPC1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL27997381 | 0.74 | TNFSF11 (0.43) | RAB9ANPC1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292242-B | Pyrantel compound and preparation, as well as preparation method and application of pyrantel compound and preparation | 广州必贝特医药技术有限公司 | 2017-05-17 | — | — | CN | claimed |
| CN-104292242-A | Pyrantel compound and preparation, as well as preparation method and application of pyrantel compound and preparation | GUANGZHOU BEBETTER MEDICINE TECHNOLOGY CO LTD | 2015-01-21 | — | — | CN | claimed |
| CN-110114647-A | Temperature detection material, temperature detection ink using same, temperature indicator, method for manufacturing temperature detection material, and article management system | 株式会社日立产机系统 | 2019-08-09 | — | — | CN | disclosed |
| CN-107074873-A | 7- (morpholinyl) -2- (N-piperazinyl) methylthioeno [2, 3-c ] pyridine derivatives as anticancer agents | 纳科法尔马有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106918995-A | Photosensitive polymer combination, photosensitive-resin layered product, resin pattern and cured film method of manufacturing pattern and display device | 旭化成株式会社 | 2017-07-04 | — | — | CN | disclosed |
| CN-104292242-B | Pyrantel compound and preparation, as well as preparation method and application of pyrantel compound and preparation | 广州必贝特医药技术有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-102971327-B | There is the anti-inflammatory compound of multiple tyrosine-kinase enzyme inhibition activity and the pharmaceutical compositions containing these compounds | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-04-20 | — | — | CN | disclosed |
| CN-102232071-B | Fused polycyclic compounds as protein kinase inhibitors | NATIONAL HEALTH RESEARCH INSTITUTES (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-105218560-A | The synthesis technique of 7-bromo-4-diuril phenol also [3,2-D] pyrimidine | SHANGHAI TITAN TECHNOLOGY CO LTD | 2016-01-06 | — | — | CN | disclosed |
| CN-102741256-B | Protein kinase is had to the bicyclic heteroaryl derivative of inhibit activities | HANMI PHARM. CO.,LTD. (KR) | 2015-12-02 | — | — | CN | disclosed |
| CN-102365277-B | JUN N-terminal kinase inhibitors | ELAN PHARMACEUTICALS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| EP-1461333-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2004-09-29 | — | — | EP | disclosed |
| CN-1437587-A | Benzoxazepinones and their use as squalene synthetase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-08-20 | — | — | CN | disclosed |
| WO-2003044009-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2003-05-30 | — | — | WO | disclosed |
| CN-1418199-A | Pyrimidine-4-one derivatives as LDL-PLA2 inhibitors | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | CN | disclosed |
| CN-1360582-A | Quinazoline derivs. | ASTRAZENECA UK LTD (GB) | 2002-07-24 | — | — | CN | disclosed |
| CN-1040213-C | Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists | MERCK FROSCT CANADA INC (CA) | 1998-10-14 | — | — | CN | disclosed |
| CN-1027369-C | Excitatory amino acid antagonists | MERRELL DOW PHARMA (US) | 1995-01-11 | — | — | CN | disclosed |
| CN-1081440-A | 2-aryl-5,6-ring-fused pyrimidines and weeding are used | ROHM & HAAS (US) | 1994-02-02 | — | — | CN | disclosed |
| CN-1047292-A | EAA antagonists | MERRELL DOW PHARMA (US) | 1990-11-28 | — | — | CN | disclosed |