Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634541 | 0.82 | KMT2A (0.36) | KDM4EHSD17B10HPGDMAPTNPC1 | |
| SCHEMBL6609300 | 0.81 | RAB9A (0.37) | KDM4EHSD17B10HPGDMAPTNPC1 | |
| SCHEMBL3672729 | 0.79 | KDM4E (0.37) | KDM4EHSD17B10HPGDMAPTNPC1 | |
| SCHEMBL10804734 | 0.79 | HPGD (0.41) | KDM4EHSD17B10HPGDMAPTNPC1 | |
| SCHEMBL9416574 | 0.78 | HDAC3 (0.39) | KDM4EHSD17B10HPGDMAPTNPC1 | |
| SCHEMBL14486887 | 0.78 | MAPT (0.37) | KDM4EHSD17B10HPGDMAPTNPC1 | |
| SCHEMBL9533816 | 0.78 | KDM4E (0.36) | KDM4EHSD17B10HPGDMAPTNPC1 | |
| SCHEMBL9409748 | 0.78 | CUL4A (0.37) | KDM4EHSD17B10HPGDMAPTNPC1 | |
| SCHEMBL11335096 | 0.77 | KEAP1 (0.36) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL3807655 | 0.76 | MEN1 (0.34) | HSD17B10MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | disclosed |
| EP-1664058-B1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006072347-A2 | ALKINYL-SUBSTITUTED THIOPHENES | AICURIS GMBH & CO. KG (DE) | 2006-07-13 | — | — | WO | disclosed |
| EP-1664058-A1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | Sanofi-Aventis Deutschland GmbH (DE) | 2006-06-07 | — | — | EP | disclosed |
| EP-1513834-B1 | SUBSTITUTED THIOPHENES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC REAGENT, AND A MEDICAMENT CONTAINING THE SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2005026173-A1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-03-24 | — | — | WO | disclosed |
| EP-1513834-A1 | SUBSTITUTED THIOPHENES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC REAGENT, AND A MEDICAMENT CONTAINING THE SAME | Aventis Pharma Deutschland GmbH (DE) | 2005-03-16 | — | — | EP | disclosed |
| EP-1440976-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-07-28 | — | — | EP | disclosed |
| EP-0927192-B1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003101984-A1 | SUBSTITUTED THIOPHENES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC REAGENT, AND A MEDICAMENT CONTAINING THE SAME | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | WO | disclosed |
| EP-1051888-B1 | PROCESS AND SOLUTION FOR THE PRELIMINARY TREATMENT OF COPPER SURFACES | ATOTECH DEUTSCHLAND GMBH (DE) | 2002-03-27 | — | — | EP | disclosed |
| EP-1055355-B1 | PROCESS FOR THE PRELIMINARY TREATMENT OF COPPER SURFACES | ATOTECH DEUTSCHLAND GMBH (DE) | 2001-12-05 | — | — | EP | disclosed |
| EP-1055355-A1 | PROCESS FOR THE PRELIMINARY TREATMENT OF COPPER SURFACES | ATOTECH Deutschland GmbH (DE) | 2000-11-29 | — | — | EP | disclosed |
| EP-1051888-A1 | PROCESS AND SOLUTION FOR THE PRELIMINARY TREATMENT OF COPPER SURFACES | ATOTECH Deutschland GmbH (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999040764-A1 | PROCESS AND SOLUTION FOR THE PRELIMINARY TREATMENT OF COPPER SURFACES | ATOTECH DEUTSCHLAND GMBH (DE) | 1999-08-12 | — | — | WO | disclosed |
| WO-1999040765-A1 | PROCESS FOR THE PRELIMINARY TREATMENT OF COPPER SURFACES | ATOTECH DEUTSCHLAND GMBH (DE) | 1999-08-12 | — | — | WO | disclosed |
| EP-0378508-B1 | Antidotes to modify the resistance of cultivated plants to agrochemical agents | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| EP-0519307-A2 | Tetracyclic Imidazodiazepines | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-23 | — | — | EP | disclosed |
| EP-0378508-A2 | Antidotes to modify the resistance of cultivated plants to agrochemical agents | CIBA-GEIGY AG (CH) | 1990-07-18 | — | — | EP | disclosed |