Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 16/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921907 | 0.88 | MCHR1 (0.80) | MCHR1HTR2C | |
| SCHEMBL6609564 | 0.87 | MCHR1 (0.73) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6605156 | 0.84 | MCHR1 (0.65) | MCHR1HTR2C | |
| SCHEMBL6603809 | 0.84 | MCHR1 (0.54) | MCHR1HTR2CKDM4ENPC1RAB9A | |
| SCHEMBL6605998 | 0.83 | MCHR1 (0.64) | MCHR1HTR2C | |
| SCHEMBL6925692 | 0.81 | MCHR1 (0.92) | MCHR1HTR2C | |
| SCHEMBL6602569 | 0.81 | MCHR1 (0.65) | MCHR1HTR2CKDM4E | |
| SCHEMBL6896989 | 0.81 | MCHR1 (0.67) | MCHR1HTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6898088 | 0.81 | MCHR1 (0.67) | MCHR1HTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6604593 | 0.80 | MCHR1 (0.57) | MCHR1HTR2CKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | claimed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | claimed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |