Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.54 |
| ▸ | BCR | P11274 | 2/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602569 | 0.90 | MCHR1 (0.65) | MCHR1HTR2CMAPT | |
| SCHEMBL6606159 | 0.90 | ALDH1A1 (0.56) | MCHR1ABL1BCRLMNAMAPT | |
| SCHEMBL6921907 | 0.90 | MCHR1 (0.80) | MCHR1HTR2C | |
| SCHEMBL6605150 | 0.88 | MCHR1 (0.75) | MCHR1HTR2C | |
| SCHEMBL6602923 | 0.85 | MCHR1 (0.64) | MCHR1HTR2CMAPT | |
| SCHEMBL6609574 | 0.84 | MCHR1 (0.63) | MCHR1HTR2C | |
| SCHEMBL6610208 | 0.83 | MCHR1 (0.63) | MCHR1ABL1BCRLMNAMAPT | |
| SCHEMBL6925692 | 0.83 | MCHR1 (0.92) | MCHR1HTR2C | |
| SCHEMBL6605998 | 0.83 | MCHR1 (0.64) | MCHR1HTR2C | |
| SCHEMBL6605102 | 0.82 | MCHR1 (0.58) | MCHR1HTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | claimed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | claimed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |