SCHEMBL6609586

SCHEMBL6609586

Cc1cc(OCCC(Cl)SC(F)(F)F)nc(Oc2ccnc(C(F)(F)F)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.34
TGFBR1 P36897 3/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 2/20 0.32
LOX P28300 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP2C19 P33261 1/20 0.31
ATM Q13315 1/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
SYK P43405 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6610026 0.86 F2RL3 (0.31)
SCHEMBL6611137 0.84 ALDH1A1 (0.41) CYP1A2CYP2C9KDM4ECYP2C19
SCHEMBL6610030 0.82 BLM (0.37) BLMTGFBR1CYP1A2CYP2C9LOX
SCHEMBL6612907 0.81 BLM (0.37) BLMTGFBR1CYP1A2CYP2C9LOX
SCHEMBL6609465 0.80
SCHEMBL6611833 0.79 KMT2A (0.40) TGFBR1
SCHEMBL6609150 0.76 BLM (0.36) BLMTGFBR1CYP1A2CYP2C9LOX
SCHEMBL6611166 0.76 BLM (0.34) BLMTGFBR1CYP1A2CYP2C9LOX
SCHEMBL8475227 0.73 CYP11B1 (0.36) BLMTGFBR1LOXLOXL2SYK
SCHEMBL6610496 0.72 L3MBTL1 (0.38) BLMLOXLOXL2KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1228062-B1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINES BASF AG (DE) 2004-04-28 EP claimed