SCHEMBL6612907

SCHEMBL6612907

Cc1cc(OCCCSC(F)(F)F)nc(Oc2ccnc(C(F)(F)F)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.37
LOXL2 Q9Y4K0 5/20 0.34
LOX P28300 2/20 0.34
TGFBR1 P36897 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
POLB P06746 1/20 0.32
ATM Q13315 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
SYK P43405 3/20 0.31
LMNA P02545 1/20 0.31
RXRA P19793 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2B Q13224 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6610030 0.94 BLM (0.37) BLMLOXL2LOXTGFBR1CYP1A2
SCHEMBL6611694 0.90 L3MBTL1 (0.38) BLMLOXL2LOXL3MBTL1POLB
SCHEMBL6609871 0.86 LOXL2 (0.37) BLMLOXL2LOXCYP1A2CYP2C9
SCHEMBL6609982 0.86 KDM4E (0.39) BLMLOXL2LOXTGFBR1KDM4E
SCHEMBL6610496 0.84 L3MBTL1 (0.38) BLMLOXL2LOXL3MBTL1POLB
SCHEMBL6610768 0.84 F2RL3 (0.30)
SCHEMBL6610274 0.82 L3MBTL1 (0.44) CYP1A2CYP2C9L3MBTL1POLBKDM4E
SCHEMBL6609586 0.81 BLM (0.34) BLMLOXL2LOXTGFBR1CYP1A2
SCHEMBL6609464 0.81 LOXL2 (0.38) BLMLOXL2LOXCYP1A2CYP2C9
SCHEMBL6611005 0.81 KDM4E (0.39) BLMLOXL2LOXTGFBR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1228062-B1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINES BASF AG (DE) 2004-04-28 EP claimed
US-6534447-B1 2,6-disubstituted pyridine derivatives in which a fluoroalkylthioalk(en)yloxy group is attached to the pyridine group in the 2-position BASF AKTIENGESELLSCHAFT (DE) 2003-03-18 US claimed
EP-1228062-A1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINES BASF AKTIENGESELLSCHAFT (DE) 2002-08-07 EP claimed
WO-2001036410-A1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINE BASF AKTIENGESELLSCHAFT (DE) 2001-05-25 WO claimed
EP-1228062-B1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINES BASF AG (DE) 2004-04-28 EP disclosed
US-6534447-B1 2,6-disubstituted pyridine derivatives in which a fluoroalkylthioalk(en)yloxy group is attached to the pyridine group in the 2-position BASF AKTIENGESELLSCHAFT (DE) 2003-03-18 US disclosed
EP-1228062-A1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINES BASF AKTIENGESELLSCHAFT (DE) 2002-08-07 EP disclosed
WO-2001036410-A1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINE BASF AKTIENGESELLSCHAFT (DE) 2001-05-25 WO disclosed