Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 12/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.62 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612491 | 0.87 | BCHE (0.56) | BCHEMAOBCCR3DRD3 | |
| SCHEMBL3233223 | 0.81 | BCHE (0.65) | BCHEMAOBCCR3ACHE | |
| SCHEMBL28192264 | 0.80 | BCHE (0.48) | BCHEMAOBACHESIGMAR1 | |
| SCHEMBL12677182 | 0.80 | BCHE (0.75) | BCHEMAOBCCR3ACHESIGMAR1 | |
| SCHEMBL6611192 | 0.79 | REV1 (0.53) | — | |
| SCHEMBL27633054 | 0.78 | ACHE (0.52) | ACHESIGMAR1 | |
| SCHEMBL28171857 | 0.75 | BCHE (0.70) | BCHEMAOBCCR3ACHE | |
| SCHEMBL12676974 | 0.74 | BCHE (0.69) | BCHEMAOBCCR3ACHEDRD2 | |
| SCHEMBL6609470 | 0.73 | BCHE (0.50) | BCHEMAOBACHECHRNA7 | |
| SCHEMBL12890021 | 0.73 | BCHE (0.69) | BCHEMAOBCCR3ACHECHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |