Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602116 | 0.86 | NCF1 (0.56) | NCF1LMNACYP1A2HIF1ACNR2 | |
| SCHEMBL27669007 | 0.80 | NCF1 (0.49) | NCF1LMNACYP1A2HIF1ACNR2 | |
| SCHEMBL6602159 | 0.77 | NCF1 (0.61) | NCF1LMNACYP1A2HIF1ACNR2 | |
| SCHEMBL6276706 | 0.76 | NCF1 (0.59) | NCF1LMNACYP1A2HIF1ACNR2 | |
| SCHEMBL5911169 | 0.75 | NCF1 (0.63) | NCF1LMNACYP1A2HIF1APTK2 | |
| SCHEMBL28746527 | 0.74 | NCF1 (0.53) | NCF1LMNACYP1A2HIF1ACNR2 | |
| SCHEMBL4783071 | 0.73 | NCF1 (0.61) | NCF1LMNACYP1A2HIF1ACNR2 | |
| Hydrochloric Acid SCHEMBL11799344 | 0.72 | NCF1 (0.59) | NCF1LMNACYP1A2HIF1ACNR2 | |
| SCHEMBL11799340 | 0.72 | NCF1 (0.59) | NCF1LMNACYP1A2HIF1ACNR2 | |
| SCHEMBL5161504 | 0.72 | ALDH1A1 (0.55) | LMNACNR2MGAMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | claimed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | claimed |