Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238748 | 0.90 | ALDH1A1 (0.56) | MAPTALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL546450 | 0.84 | ALDH1A1 (0.64) | MAPTALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL30061320 | 0.84 | ALDH1A1 (0.64) | MAPTALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL14941460 | 0.83 | ALDH1A1 (0.59) | MAPTALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL6609562 | 0.80 | ALDH1A1 (0.59) | MAPTALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL16054038 | 0.80 | ALDH1A1 (0.59) | MAPTALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL29710198 | 0.80 | ALDH1A1 (0.59) | MAPTALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL6202441 | 0.80 | MAPT (0.54) | MAPTALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL29788525 | 0.80 | HTT (0.59) | MAPTALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL24269287 | 0.78 | MAPT (0.46) | MAPTALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456208-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-15 | — | — | EP | disclosed |
| US-20040106596-A1 | Pyridoquinoxaline antivirals | PERRAULT WILLIAM R (US) | 2004-06-03 | — | — | US | disclosed |
| US-6686356-B2 | HERPES VIRUS | PHARMACIA & UPJOHN COMPANY | 2004-02-03 | — | — | US | disclosed |
| US-20030130255-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY | 2003-07-10 | — | — | US | disclosed |
| WO-2003053972-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106596-A1 | Pyridoquinoxaline antivirals | IFNAR1, ZC3HAV1, SARS1 | MAPT 4339/4885ALDH1A1 803/4885LMNA 4453/4885 |
| US-20030130255-A1 | PYRIDOQUINOXALINE ANTIVIRALS | IFNAR1, ZC3HAV1, SARS1 | MAPT 4339/4885ALDH1A1 803/4885LMNA 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.