Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881189 | 0.78 | GAA (0.49) | GAACHEK1PARP1TTKDYRK1A | |
| SCHEMBL11056583 | 0.78 | SRC (0.37) | MAPTGAAKDM4EPOLBRECQL | |
| SCHEMBL11841387 | 0.78 | ALDH1A1 (0.39) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL10882635 | 0.78 | MAPK1 (0.41) | MAPTKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL2260820 | 0.77 | KDM4E (0.32) | MAPTKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL11843467 | 0.73 | NOS1 (0.47) | MAPTGAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL18306 | 0.72 | ACHE (0.41) | IMPDH2IMPDH1MAPTGAAKDM4E | |
| SCHEMBL29521417 | 0.72 | ACHE (0.41) | IMPDH2IMPDH1MAPTGAAKDM4E | |
| SCHEMBL9065359 | 0.71 | ACHE (0.40) | IMPDH2IMPDH1MAPTGAAKDM4E | |
| SCHEMBL6827565 | 0.71 | ACHE (0.40) | IMPDH2IMPDH1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395584-A4 | URONIUM AND IMMONIUM SALTS FOR PEPTIDE COUPLING | CARPINO LOUIS A (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1395584-A1 | URONIUM AND IMMONIUM SALTS FOR PEPTIDE COUPLING | Carpino, Louis A. (US) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094822-A1 | URONIUM AND IMMONIUM SALTS FOR PEPTIDE COUPLING | CARPINO LOUIS A (US) | 2002-11-28 | — | — | WO | disclosed |
| WO-1996024617-A1 | DESAMINONONAPEPTIDES, PROCESS FOR PREPARING THE SAME AND THEIR USE FOR PREPARING ELCATONIN | LONZA AG (CH) | 1996-08-15 | — | — | WO | disclosed |
| US-5262331-A | Method for monitoring in peptide synthesis | CALBIOCHEM NOVABIOCHEM CORP | 1993-11-16 | — | — | US | disclosed |
| EP-0440783-A1 | A METHOD FOR MONITORING IN PEPTIDE SYNTHESIS BY ACYLATION REACTION BETWEEN AN ACTIVATED CARBOXYLIC ACID DERIVATIE AND AN AMINE | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1991-08-14 | — | — | EP | disclosed |
| WO-1991003485-A1 | A METHOD FOR MONITORING IN PEPTIDE SYNTHESIS | NOVABIOCHEM AG (CH) | 1991-03-21 | — | — | WO | disclosed |
| EP-0064714-A1 | Process for desensitizing hydroxybenzotriazoles and hydroxy-oxobenzotriazines | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-17 | — | — | EP | disclosed |