Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | KIT | P10721 | 1/20 | 0.73 |
| ▸ | GABRP | O00591 | 1/20 | 0.65 |
| ▸ | GABRD | O14764 | 1/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.65 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.65 |
| ▸ | CCNC | P24863 | 1/20 | 0.65 |
| ▸ | CDK2 | P24941 | 1/20 | 0.65 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.65 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31383399 | 0.90 | ALDH1A1 (0.69) | ALDH1A1MAPTKDM4EGAAKIT | |
| SCHEMBL10013320 | 0.85 | ABCB1 (0.64) | ALDH1A1MAPTKDM4EGAAKIT | |
| SCHEMBL30764599 | 0.84 | ALDH1A1 (0.85) | ALDH1A1MAPTKDM4EGAAKIT | |
| SCHEMBL4626785 | 0.84 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4EGAAKIT | |
| SCHEMBL8160531 | 0.83 | ALDH1A1 (0.82) | ALDH1A1MAPTKDM4EGAAKIT | |
| SCHEMBL26112503 | 0.82 | PPARG (0.81) | ALDH1A1MAPTKDM4EGAAKIT | |
| SCHEMBL27939886 | 0.82 | ALDH1A1 (0.76) | ALDH1A1MAPTKDM4EGAAKIT | |
| SCHEMBL29187274 | 0.81 | ALDH1A1 (0.76) | ALDH1A1MAPTKDM4EGAAKIT | |
| Sideroxylin SCHEMBL28397284 | 0.80 | PPARG (0.73) | ALDH1A1MAPTKDM4EGAAGABRP | |
| Wogonin SCHEMBL29632729 | 0.79 | GABRP (1.00) | ALDH1A1MAPTKDM4EGAAKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | CHOONG ANG VACCINE LAB. (KR) | 2012-02-23 | — | — | US | disclosed |
| WO-2012023660-A1 | ANTIVIRAL DRUG FOR AVIAN AND SWINE INFLUENZA AND NOVEL FLU, OBTAINED FROM CLEISTOCALYX OPERCULATUS | 주식회사 중앙백신연구소 (KR) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | PIGS, CLEC4M, ENGASE | ALDH1A1 2216/4885MAPT 2192/4885KDM4E 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.