Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610652 | 0.90 | L3MBTL1 (0.39) | HSD17B10ATMSYKCAPN1LMNA | |
| SCHEMBL6773117 | 0.89 | SYK (0.42) | ATMSYKCTSLLMNACTSS | |
| SCHEMBL6610959 | 0.78 | ATM (0.43) | HSD17B10ATMCAPN1CTSLCTSS | |
| SCHEMBL25061660 | 0.71 | TACR1 (0.38) | HSD17B10SMN1; SMN2 | |
| SCHEMBL25400656 | 0.71 | ADAM17 (0.38) | HSD17B10SMN1; SMN2 | |
| SCHEMBL7378563 | 0.70 | SYK (0.57) | HSD17B10SYKCTSLLMNASMN1; SMN2 | |
| SCHEMBL25398090 | 0.70 | TACR1 (0.37) | HSD17B10SMN1; SMN2 | |
| SCHEMBL27339025 | 0.70 | HSD17B10 (0.52) | HSD17B10ATMSYKCTSLLMNA | |
| SCHEMBL6611623 | 0.69 | TSHR (0.40) | HSD17B10ATMSYKLMNAMAPK1 | |
| SCHEMBL18086889 | 0.68 | CTSK (0.55) | HSD17B10SYKCTSLLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212309-B1 | CASPASE INHIBITOR | LG CHEM INVESTMENT LTD (KR) | 2004-08-18 | — | — | EP | disclosed |
| US-6747050-B1 | INHIBITING THE ACTIVITY OF CASPASES, PREVENTING INFLAMMATION AND APOPTOSIS | LG CHEM INVESTMENT LTD. (KR) | 2004-06-08 | — | — | US | disclosed |