Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 8/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611409 | 0.92 | CCR5 (0.45) | KMT2ACXCR3CCR5TACR1MEN1 | |
| SCHEMBL6610820 | 0.91 | CCR5 (0.51) | KMT2ACXCR3CCR5TACR1MEN1 | |
| SCHEMBL6613828 | 0.91 | CCR5 (0.49) | KMT2ACXCR3CCR5TACR1MEN1 | |
| SCHEMBL6614319 | 0.90 | CCR5 (0.52) | KMT2ACXCR3CCR5TACR1MEN1 | |
| SCHEMBL6612135 | 0.90 | CCR5 (0.52) | KMT2ACXCR3CCR5TACR1MEN1 | |
| SCHEMBL6614375 | 0.89 | KMT2A (0.43) | KMT2ATACR1MEN1L3MBTL1TNF | |
| SCHEMBL6612019 | 0.89 | MAPT (0.46) | KMT2ATACR1MEN1L3MBTL1 | |
| SCHEMBL6615823 | 0.88 | CXCR3 (0.61) | CXCR3CCR5 | |
| SCHEMBL6613290 | 0.87 | CCR5 (0.62) | KMT2ACXCR3CCR5TACR1MEN1 | |
| SCHEMBL2086680 | 0.84 | CXCR3 (0.69) | CXCR3CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236726-B1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1236726-A1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-09-04 | — | — | EP | disclosed |