SCHEMBL6612640

SCHEMBL6612640

N#Cc1cc(OCCCSC(F)(F)F)nc(Oc2ccnc(OC(F)F)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
GRM5 P41594 2/20 0.32
PTGES O14684 1/20 0.31
ALOX5 P09917 1/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6610974 0.95 KDM4E (0.33) KDM4ELMNAGRM5PTGESALOX5
SCHEMBL6610717 0.87 ATP1A1 (0.32)
SCHEMBL6610768 0.87 F2RL3 (0.30)
SCHEMBL6609982 0.85 KDM4E (0.39) KDM4ELMNAGRM5
SCHEMBL6612235 0.85 LMNA (0.31) LMNA
SCHEMBL6610955 0.82 F2RL3 (0.33)
SCHEMBL6611301 0.82 ATP1A1 (0.33) KDM4ELMNA
SCHEMBL6611005 0.80 KDM4E (0.39) KDM4ELMNAGRM5
SCHEMBL6611243 0.79
SCHEMBL6615326 0.79 POLB (0.42) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1228062-B1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINES BASF AG (DE) 2004-04-28 EP claimed
US-6534447-B1 2,6-disubstituted pyridine derivatives in which a fluoroalkylthioalk(en)yloxy group is attached to the pyridine group in the 2-position BASF AKTIENGESELLSCHAFT (DE) 2003-03-18 US claimed
EP-1228062-B1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINES BASF AG (DE) 2004-04-28 EP disclosed
US-6534447-B1 2,6-disubstituted pyridine derivatives in which a fluoroalkylthioalk(en)yloxy group is attached to the pyridine group in the 2-position BASF AKTIENGESELLSCHAFT (DE) 2003-03-18 US disclosed
EP-1228062-A1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINES BASF AKTIENGESELLSCHAFT (DE) 2002-08-07 EP disclosed
WO-2001036410-A1 HERBICIDAL 2-ARYLOXY-6-FLUOROALKYLTHIOALK(EN)YLOXY-PYRIDINE BASF AKTIENGESELLSCHAFT (DE) 2001-05-25 WO disclosed