Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NCF1 | P14598 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617070 | 0.86 | NQO2 (0.38) | RENALDH1A1NCF1MAPTHSD17B10 | |
| SCHEMBL9283316 | 0.65 | TLR8 (0.43) | ALDH1A1TSHRNUDT1KDM4E | |
| SCHEMBL20495242 | 0.64 | SMN1; SMN2 (0.44) | ALDH1A1MAPTHSD17B10CASP1CASP7 | |
| SCHEMBL6616973 | 0.63 | NCF1 (0.59) | ALDH1A1NCF1HSD17B10CASP1CASP7 | |
| SCHEMBL8559919 | 0.60 | POLB (0.43) | ALDH1A1NCF1MAPTHSD17B10CASP1 | |
| SCHEMBL20494897 | 0.60 | KDM4E (0.36) | HSD17B10KDM4E | |
| SCHEMBL5358262 | 0.60 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL6416089 | 0.59 | NPSR1 (0.51) | MAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL6416704 | 0.59 | TLR8 (0.39) | — | |
| SCHEMBL12005742 | 0.59 | ALDH1A1 (0.34) | ALDH1A1MAPTHSD17B10TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |