Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613342 | 0.86 | REN (0.34) | RENKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL5358262 | 0.74 | ALDH1A1 (0.42) | NQO2TLR8TLR7ALDH1A1HSD17B10 | |
| SCHEMBL1857081 | 0.71 | ACHE (0.49) | NQO2LMNAKMT2AMEN1TERT | |
| SCHEMBL6613348 | 0.68 | NQO2 (0.75) | NQO2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL27931468 | 0.68 | KDM4E (0.46) | NQO2LMNAKMT2AMEN1TLR8 | |
| SCHEMBL9283316 | 0.67 | TLR8 (0.43) | LMNATLR8TLR7KDM4EALDH1A1 | |
| SCHEMBL24166490 | 0.66 | ALDH1A1 (0.60) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL30656860 | 0.66 | ALDH1A1 (0.60) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL20495242 | 0.66 | SMN1; SMN2 (0.44) | LMNAKMT2AMEN1THRBKDM4E | |
| SCHEMBL5873661 | 0.65 | TLR8 (0.46) | NQO2LMNAKMT2AMEN1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |