Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612097 | 0.91 | MEN1 (0.55) | MEN1KMT2ACYP1A2CYP2C19NPC1 | |
| SCHEMBL6646533 | 0.86 | KMT2A (0.54) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL7736656 | 0.86 | POLB (0.43) | MEN1KMT2ACYP1A2CYP2C19NPC1 | |
| SCHEMBL6616633 | 0.84 | SMN1; SMN2 (0.50) | MEN1KMT2ACYP1A2CYP2C19NPC1 | |
| SCHEMBL4682013 | 0.82 | CTSB (0.46) | CXCR3MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL4682015 | 0.82 | CTSB (0.46) | CXCR3MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL6611355 | 0.80 | KCNJ11 (0.42) | MEN1KMT2ACYP1A2CYP2C19MAPT | |
| SCHEMBL7742482 | 0.79 | MEN1 (0.52) | MEN1KMT2ANPC1MAPTNPSR1 | |
| SCHEMBL6612989 | 0.78 | RXFP1 (0.52) | MEN1KMT2ACYP2C19MAPTHTT | |
| SCHEMBL6612032 | 0.78 | KMT2A (0.49) | MEN1KMT2ACYP2C19NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392655-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2004-03-03 | — | — | EP | claimed |
| JP-2003506355-A | — | — | 2003-02-18 | — | — | JP | claimed |
| WO-2002062762-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | claimed |
| EP-1198456-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-24 | — | — | EP | claimed |
| WO-2001009096-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-02-08 | — | — | WO | claimed |
| EP-1392655-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002062762-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | disclosed |