Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612097 | 0.87 | MEN1 (0.55) | KMT2AHTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL6613372 | 0.86 | CXCR3 (0.46) | KMT2AHTTMAPTMEN1MAPK1 | |
| SCHEMBL7741529 | 0.86 | ABCC9 (0.58) | KMT2ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL4682722 | 0.83 | ABCC9 (0.53) | KMT2AHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4682724 | 0.83 | ABCC9 (0.53) | KMT2AHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6616633 | 0.81 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL7742284 | 0.79 | ABCC9 (0.54) | KMT2ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL6644906 | 0.79 | KCNJ11 (0.40) | KMT2ANAMPT | |
| SCHEMBL7145794 | 0.79 | KCNJ11 (0.44) | NAMPT | |
| SCHEMBL11629091 | 0.78 | KMT2A (0.80) | KMT2AHTTSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392655-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002062762-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | disclosed |