Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613370 | 0.89 | L3MBTL1 (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL3700318 | 0.87 | L3MBTL1 (0.47) | SMN1; SMN2POLBBRD4ALDH1A1 | |
| SCHEMBL6614270 | 0.87 | ACHE (0.44) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL2719198 | 0.85 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL3669603 | 0.85 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL6611026 | 0.83 | HPGD (0.53) | SMN1; SMN2POLBATMHPGDALDH1A1 | |
| SCHEMBL692642 | 0.82 | HSD17B10 (0.37) | POLBAPEX1BLMALDH1A1 | |
| SCHEMBL688493 | 0.82 | POLB (0.60) | POLBALDH1A1 | |
| SCHEMBL7275276 | 0.81 | DPP4 (0.48) | SMN1; SMN2POLBATMHPGDALDH1A1 | |
| SCHEMBL2709981 | 0.80 | CYP3A4 (0.37) | SMN1; SMN2POLBBRD4HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2971064-B1 | PROXIMITY ASSAY FOR IN SITU DETECTION OF TARGETS | VENTANA MED SYST INC (US) | 2019-10-16 | — | — | EP | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-1112271-A1 | ERGOLINE AMINE DERIVATIVES WITH BLOOD PRESSURE LOWERING EFFECT | Cybio Screening GmbH (DE) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000004018-A1 | ERGOLINE AMINE DERIVATIVES WITH BLOOD PRESSURE LOWERING EFFECT | CYBIO SCREENING GMBH (DE) | 2000-01-27 | — | — | WO | disclosed |