Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616444 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AATMSLC6A4 | |
| SCHEMBL6615932 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AATMSLC6A4 | |
| SCHEMBL6612859 | 0.88 | HTR1A (0.60) | ALDH1A1MEN1KMT2ASLC6A4HTR1A | |
| SCHEMBL6615657 | 0.87 | HTR1A (0.49) | ALDH1A1MEN1KMT2AATMSLC6A4 | |
| SCHEMBL6613554 | 0.86 | HTR1A (0.49) | ALDH1A1MEN1KMT2AATMSLC6A4 | |
| SCHEMBL6614326 | 0.85 | SLC6A4 (0.42) | ALDH1A1ATMSLC6A4SLC6A2HTT | |
| SCHEMBL6416394 | 0.84 | ALDH1A1 (0.46) | ALDH1A1ATMSLC6A4SLC6A2HTT | |
| SCHEMBL6414736 | 0.84 | ALDH1A1 (0.46) | ALDH1A1ATMSLC6A4SLC6A2HTT | |
| SCHEMBL6615152 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AATMSLC6A4 | |
| SCHEMBL6617668 | 0.81 | SLC6A4 (0.46) | ALDH1A1ATMSLC6A4SLC6A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |