Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612859 | 0.91 | HTR1A (0.60) | HTR1ASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6616238 | 0.91 | HTR1A (0.49) | HTR1ASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6613554 | 0.89 | HTR1A (0.49) | HTR1ASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6614493 | 0.87 | HTR1A (0.46) | HTR1ASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6613622 | 0.87 | ALDH1A1 (0.45) | HTR1ASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6409933 | 0.86 | HTR1A (0.51) | HTR1ASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6413344 | 0.86 | HTR1A (0.51) | HTR1ASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6616444 | 0.85 | ALDH1A1 (0.44) | HTR1ASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6614573 | 0.84 | SLC6A4 (0.51) | HTR1ASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6615400 | 0.83 | HTR1A (0.51) | HTR1ASLC6A4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |