Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.41 |
| ▸ | F2 | P00734 | 7/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967893 | 0.72 | F10 (0.49) | F10PRSS1F2F9 | |
| SCHEMBL6616732 | 0.69 | F10 (0.78) | F10PRSS1F2F9 | |
| SCHEMBL1829208 | 0.62 | RXFP1 (0.50) | GAAKMT2A | |
| SCHEMBL6613306 | 0.62 | F2 (0.56) | F10CA1CA2PRSS1F2 | |
| SCHEMBL21239986 | 0.61 | CA2 (0.63) | CA1CA2MEN1KMT2A | |
| SCHEMBL29821990 | 0.61 | CA2 (0.63) | CA1CA2MEN1KMT2A | |
| SCHEMBL7933999 | 0.60 | CA1 (0.73) | CA1CA2 | |
| SCHEMBL12673440 | 0.60 | MEN1 (0.46) | MEN1GAAKMT2A | |
| SCHEMBL1080972 | 0.58 | CA2 (0.61) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL20772514 | 0.58 | MAPT (0.62) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015429-B1 | BENZIMIDAZOLINONES, BENZOXAZOLINONES, BENZOPIPERAZINONES, INDANONES, AND DERIVATIVES THEREOF AS INHIBITORS OF FACTOR XA | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-05-12 | — | — | EP | claimed |