Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 18/20 | 0.49 |
| ▸ | F2 | P00734 | 14/20 | 0.49 |
| ▸ | F9 | P00740 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616732 | 0.73 | F10 (0.78) | F10PRSS1F2F9PLG | |
| SCHEMBL6614149 | 0.72 | F10 (0.43) | F10PRSS1F2F9 | |
| SCHEMBL8019749 | 0.66 | F10 (1.00) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL7438112 | 0.64 | F10 (0.59) | F10PRSS1F2F9PLG | |
| SCHEMBL12132476 | 0.64 | F10 (0.75) | F10PRSS1PLGPLATKLK1 | |
| SCHEMBL8019753 | 0.64 | F10 (0.66) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL8032829 | 0.64 | F10 (1.00) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL7361157 | 0.64 | F10 (0.64) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL7059969 | 0.62 | F10 (0.49) | F10PRSS1F2PLGPLAT | |
| SCHEMBL12132413 | 0.62 | F10 (0.66) | F10PRSS1PLGPLATKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207697-B1 | AMIDINYL-SUBSTITUTED RINGS; ANTICOAGULANTS; THROMBOEMBOLIC DISORDERS; ANTIISCHEMIC AND ANTIINFLAMMATORY AGENTS; STROKES; SERINE PROTEASE INHIBITORS | DUPONT PHARMACEUTICALS COMPANY | 2001-03-27 | — | — | US | disclosed |