Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 13/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614632 | 0.91 | SLC6A4 (0.40) | SLC6A4SLC6A2HTR1AACHEDRD2 | |
| SCHEMBL6615341 | 0.89 | SLC6A4 (0.42) | SLC6A4HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL6614898 | 0.87 | HTR1A (0.59) | SLC6A4HTR1A | |
| SCHEMBL6615152 | 0.86 | ALDH1A1 (0.47) | SLC6A4SLC6A2HTR1AACHE | |
| SCHEMBL6616451 | 0.85 | HTR1A (0.49) | SLC6A4HTR1A | |
| SCHEMBL6417415 | 0.85 | SLC6A4 (0.44) | SLC6A4SLC6A2HTR1AACHE | |
| SCHEMBL6411104 | 0.85 | SLC6A4 (0.44) | SLC6A4SLC6A2HTR1AACHE | |
| SCHEMBL6615662 | 0.85 | HTR1A (0.49) | SLC6A4HTR1A | |
| SCHEMBL6618608 | 0.82 | SLC6A4 (0.42) | SLC6A4SLC6A2HTR1A | |
| SCHEMBL6614326 | 0.81 | SLC6A4 (0.42) | SLC6A4SLC6A2HTR1AACHEDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |